Liposomal encapsulation provides enhanced protection against environmental stressors
Ann Surg Oncol 22(3):834-42, 2015
Clinical features Beriberi: inadequate thiamine uptake due to malnutrition, heavy drinking, or increased demand (e.g., hyperthyroidism, pregnancy) Dry beriberi Symmetrical peripheral neuropathy (sensory and motor) Progressive muscle wasting Paralysis Confusion Wet beriberi High-output cardiac failure (due to systemic vasodilation) Dilated cardiomyopathy Cardiomegaly Edema Infantile beriberi: cardiomegaly, tachycardia, cyanosis, aseptic meningitis (vomiting and seizures) Wernicke encephalopathy Leigh syndrome Diagnostics: vitamin B 1 administration RBC transketolase activity In malnourished or alcohol-dependent patients, always administer thiamine before giving dextrose to decrease the risk of precipitating or exacerbating Wernicke encephalopathy
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Cancer 120 (20), 32083218
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