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This regulatory mechanism ensures that ferritinophagy mediated by NCOA4 adapts to the cellular iron status and environmental cues, maintaining iron homeostasis and shielding cells from oxidative stress due to uncontrolled iron release
Aptamers against live targets: is in vivo SELEX finally coming to the edge
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Our metabolic analyses showed that Gclc deficiency led to an accumulation of succinate, indicating a block in the TCA cycle
Second is the NADPH-dependent small ETC, composed of NADH and Cyt b localized in the peroxisomal membrane which utilizes O 2 as the electron acceptor and releases O 2 into the cytosol
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