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For example, deferiprone (DFP) and PBT2 have been shown to increase endothelial tight junction protein expression in AD models, reduce vascular leakage, and improve BBB integrity, suggesting an indirect BBB-protective potential (Ayton et al., 2025)

The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression

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YCWLP could alleviate the severity of CCl4-induced liver fibrosis by reshaping the gut microbiotaby regulating bacterial genera (such as Christensenella , Ruminococcus , and Barnesiella ) associated with liver fibrosis

Visualization of the metaphase II meiotic spindle in living human oocytes using the Polscope enables the prediction of embryonic developmental competence after ICSI

KUMAR, Premranjan et al