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The results showed a significant increase in the number of TUNEL-positive points in senescent endothelial cells treated with FOXO4-DRI

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StephenBJChokriwalASharmaMMJainDSaxenaJDhaliwalHet al

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However, their effects are variable and generally observed in only a minority of patients, making it challenging to predict treatment efficacy on an individual basis [9]

Several considerations are typically accounted for, besides accurate mass and RT, which includes the elimination of background signals, deisotoping, identification of adduct peaks in MS spectra, and MS/MS fragmentation patterns compared to databases or internal standards and the matching degree estimated (see Figure 2)