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PACE selections have been used to reprogramme the specificity of diverse proteins, including DNA-binding domains, antibody mimetics, degron tags and catalysts including polymerases, aminoacyl-tRNA synthetases, dehydrogenases and proteases 2,6,7,8,9,10,11,12

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doi: 10.3389/fpsyt.2022.926688 Received 22 April 2022 Accepted 16 May 2022 Published 20 June 2022 Volume 13 - 2022 Edited by Roumen Milev, Queen's University, Canada Reviewed by Julia Rucklidge, University of Canterbury, New Zealand

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