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GLP-1 is a hormone naturally produced in your gut that regulates appetite, blood sugar, and digestion, making it a crucial component for sustainable weight loss

In the brain, the interaction of GLP-1 or GLP-1RA with the GLP-1R additionally contributes to multi-level control of neuroplasticity mechanisms thus having potential cognitive and affective effects

3A), whereas the mRNA levels of the adipogenesis-related genes, such as ACC, FAS , and DGAT2 , were significantly decreased (Fig

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doi: 10.1056/NEJMoa2116185 [DOI] [PMC free article] [PubMed] [Google Scholar] 16