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Additionally, FINO2, an endogenous peroxidase 1, 2-dioxygenase, induces ferroptosis in tumor cells by oxidizing iron and inactivating GPX4 [130]

Conclusions In these studies, within the limitations of small sample sizes, no clinically relevant differences in cagrilintide pharmacokinetics were observed in participants with renal or hepatic impairment compared with those with normal function, suggesting that dose adjustment is not warranted for these populations

MedranoEscalada Y, PlazaManzano G, FernandezdeLasPenas C, ValeraCalero JA

Hoshida S, Yamashita N, Igarashi J, et al

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Gregori, L., Poosch, M