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Caloric restriction in growing children, whether from appetite suppression or intentional dietary changes, can impair bone mineral density accrual if calcium and vitamin D intake falls below recommended thresholds

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In a 68-week clinical trial targeting weight reduction and long-term maintenance in pediatric patients aged 12 years and older with obesity, more patients treated with Wegovy achieved a greater than 5% reduction in baseline BMI compared to those treated with placebo

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