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human evidence is limited, the combination is unvalidated, and individual results vary

The body adopts a series of regulatory measures to adapt to this change, such as promoting the synthesis process of carnitine and increasing the activity or expression level of carnitine synthases to increase the production of endogenous carnitine

Without adequate L-Carnitine, the transport of these fatty acids is severely hampered, leading to a reduced capacity for fat utilization as an energy source

Source data have also been published for the Figures and Extended Data Figures as per journal policy

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Indeed, the pediatric autoimmune neuropsychiatric disorder associated with group A -hemolytic streptococcus (GABHS) (PANDAS) and thus the recalled pediatric acute neuropsychiatric syndrome (PANS) have highlighted that several agents rather than streptococcus could be involved in these acute-onset forms of OCD 48