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Overuse of active ingredients: combining acids, retinoids, vitamin C, peptides, AHAs, and BHAs all at once

Semaglutide trials showed an average weight loss of approximately 15%, indicating that the medication alters baseline physiology but typically requires ongoing support to sustain results

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Severe allergic reactions: Though rare, symptoms like facial swelling, trouble breathing, or a full-body rash need emergency attention

Thirdly, gastrointestinal effects represent another consideration

Mounjaro faces competition from other GLP-1 RAs, notably Novo Nordisk's semaglutide, but has shown superiority in head-to-head trials