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This mechanism contributes to constipation in approximately 24% of patients in clinical trials

The guidelines ( A new MRA, finerenone, was found to express some cardioprotective effects in patients with chronic kidney disease (CKD) and T2DM (165167), although it is currently indicated for CKD in T2DM only

It is a hormone produced primarily in the small intestine (specifically in the L cells which line this part of your digestive tract), though some neurons in your brain also produce it

When three signaling pathways are being investigated simultaneously, any such off-target effect from an unknown contaminant can make the resulting data impossible to interpret

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