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Due to the retrospective study design, standardized assessments of lifestyle factors (dietary intake and physical activity) were unavailable in the source dataset

SacksFMSvetkeyLPVollmerWMAppelLJBrayGAHarshaDet alEffects on blood pressure of reduced dietary sodium and the dietary approaches to stop hypertension (DASH) diet

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For the identification of rare serious adverse events that do manifest for years or decades following clinical trial, only broad scale and careful tracking of outcomes can indicate side effect probability in a diverse population, though through careful trial design, the number of patients required for a complete analysis of safety within various demographics can be minimized