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Plant-derived 5-HT/MT exhibits favorable bioactivity profiles, facilitating safe consumption without adverse effects 5

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Remarkably, this inflammation-targeting SP@M restored osteoimmunology homeostasis, inhibited the activation of osteoclasts, protected bone formation, and promoted cartilage recovery in CIA mouse models in vivo (Fig

In contrast, increased cell death was consistently observed across various lymphoid cell types, including tumor cells, underscoring that, within 3D gels, cell death, rather than cell cycle arrest, impedes lymphoid cell growth