Statistical analysis Using data generated from a pilot study and G*Power 3.1 software (Dsseldorf, Germany), it was determined that a sample size of 15 would provide 80% power to detect an increase in CNS GSH concentrations between pre- and post-administration values, with an accepted alpha value of 0.2
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However, further randomized control studies are needed to evaluate and confirm the efficacy of ALA as a potential adjuvant therapy in COVID-19 infection
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