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Twenty l of filtered MTT solution (5 mg/ml in PBS) was added to each well, after which the plates were incubated for an additional 4 h

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Glycation products The level of APs was significantly lower in Fru + amlodipine (35%), Fru + aminoguanidine (37%), and Fru + NAC (42%) compared to Fru

When oxidative stress is left unchecked, it can lead to the formation of harmful substances that damage blood vessels, contributing to conditions like atherosclerosis and high blood pressure

Moreover, some pharmaceutical excipients, diluents or carriers are potentially ototoxic