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Supplementation with CoQ 10 confers protection against the progression of oxidative damage and mitochondrial dysfunction in Down syndrome patients (Tiano and Busciglio, Neurodegenerative diseases Mitochondrial dysfunction has been associated with the onset and/or development of neurodegenerative diseases (Arun et al., 10 may protect against neuronal damage caused by ischemia, atherosclerosis, and toxic injury (Ishrat et al., 10 and -tocopherol and higher levels of lipoprotein oxidation in the plasma and cerebrospinal fluid compared to non-affected individuals (Buhmann et al., 10 deficiency was observed at a higher frequency in Parkinson's disease, underscoring its utility as a peripheral biomarker (Mischley et al., 10 supplementation could benefit patients suffering from neurodegenerative diseases

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J Pediatr 119:491493

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