Lower initial exposure may reduce early side effects, and improved tolerability can make it easier for patients to remain on therapy long enough to evaluate its benefits
As a result, LC-MS has become a critical analytical tool in the development, quality control, and regulatory evaluation of peptide therapeutics
But in the specific context of GLP-1 receptor agonist therapy, testosterone's role becomes particularly consequential, for a reason that goes to the heart of what these medications are actually trying to achieve
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Greenberg BH, Abraham WT, Albert NM, Chiswell K, Clare R, Stough WG, et al
Furthermore, to examine which factors independently determine GLP-1 receptor expression in the intima and media, we performed multivariate analyses