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Safety is a critical factor to consider when evaluating long-term cardiometabolic therapies

Specifically, semaglutide increases levels of incretins, which are hormones produced naturally by the stomach during eating, thereby increasing insulin levels when needed

In study 1, the mean baseline HbA1c was 7.5%, and 12% of patients were on insulin therapy

By doing this, it helps the heart beat more slowly and with less force, which in turn lowers blood pressure

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The anti-diabetic actions of semaglutide include stimulation of insulin secretion, inhibition of glucagon secretion after meals and delay of gastric emptying [8]