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POPs are mainly excreted through conjugation with GSH and this mechanism is extremely important for the health status, since exposure to POPs has been associated to diabetes, cardiovascular diseases and many other chronic diseases ( ROS production can occur at several intracellular sites but, for most cells, takes place in the mitochondria and the mitochondrial electron transport chain is the main cellular process of ROS generation in physiological circumstances ( 2 O 2 )

Knoth R, Singec I, Ditter M, Pantazis G, Capetian P, Meyer RP, et al

The hypothesized linkage between the action of AngFV analogues and the HGF/c-Met system predicted that like Dihexa and Nlel -AnglV HGF should be able to stimulate dendritic spine growth in dissociated hippocampal neurons

It has mitochondrial effects

PTD-DBM a next-generation peptide helps support visible scalp rejuvenation by promoting a healthy-looking environment around the follicles

Dihexa's primary mechanism is activation of the HGF/c-Met signaling pathway (hepatocyte growth factor / its receptor c-Met)