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The in vitro cytotoxicity (MTT assay after 24 h) of free curcumin (IC 50 = 39.6 2.4 M) in the multidrug-resistant human colon adenocarcinoma cell line (COLO-320/MDR-LRP) was not enhanced by the formation of [Rh( 5 -C 5 Me 5 )(curcumin)(H 2 O)] + (IC 50 = 34.8 0.2 M)

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