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This modulation of inflammatory signaling occurs through activation of the PI3K/AKT pathway, which possesses intrinsic anti-inflammatory properties including inhibition of pro-inflammatory cytokine release and enhancement of cellular stress resistance
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Cancer cachexia will lead to a reduced tolerance of cancer treatment, a poorer quality of life and decreased survival [3, 4]
doi: 10.1074/jbc.M703091200 88 FrancoR.SchoneveldO
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