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Allard C, Doyon M, Brown C, Carpentier AC, Langlois MF, Hivert MF

doi:10.1001/jama.2023.12876 Gaskins AJ, Mumford SL, Chavarro JE, et al

Mouse models of diabetic nephropathy

25 2025, Published 8:00 a.m

However, further research is needed to validate these findings in larger, more diverse populations and over a longer period of time

Recently, the exercise-induced microRNA miR-129-3p has been proposed as a promising candidate for exercise mimetics, as it maintains muscle integrity via the PARP1SIRT1PGC1 axis and ameliorates muscle atrophy and mitochondrial dysfunction.[86] Electrical pulse stimulation (EPS) has been used to mimic muscle contraction in myotubes and induce transcriptional changes comparable to in vivo exercise