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This is attributed to the loss of MT stabilization and even destabilization of MTs, and also destabilizing interactions with actin filaments, as the phosphorylation of Tau at specific sites reduces the capacity of Tau to bind MTs that contributes to neuronal structural instability and neurodegeneration (Johnson and Stoothoff, 2004

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They also provide natural sources of zinc, copper, manganese, and potassium, all of which contribute to bone strength, enzyme function, and overall well-being in dogs