Gastric cancer tumor growth was partially reversed after -KG supplementation
CJC-1295 with DAC includes an added Drug Affinity Complex that binds to blood proteins, extending its activity window for days
doi: 10.3390/antiox9050440
This study was funded by the National Natural Science Foundation of China (82474560, 82104914), the Natural Science Foundation of Shandong Province of China (ZR2023MH112), 2024 Shenzhen Luohu District Soft Science Research Program (LX202402023)
In a rat model, our previous research on early NHPN-1010 treatment for blast-induced tinnitusspecifically targeting cochlear synaptopathydemonstrated that (1) blast overpressure caused a permanent loss of cochlear nerve ribbon synapses (RSs), and (2) administration of NHPN-1010 within 3 days of blast trauma, compared to placebo, significantly rescued RSs, as evidenced by ribbon counts in cochlear histological analyses and corresponding functional changes in suprathreshold wave-I amplitudes of the auditory brainstem response (ABR) 34
PEG-T ECM -NS activated immunogenicity of tumour cells We further evaluated the efficacy of PEG-T ECM -NS/OLE-induced immunogenicity of the tumour cells and the ability to turn the tumour cells into antigen-presenting cells (APC) via ICD