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Wegovy (semaglutide 2.4 mg) can generally be taken safely after gallbladder removal, and having undergone cholecystectomy is not listed as a contraindication to treatment in the Summary of Product Characteristics approved by the Medicines and Healthcare products Regulatory Agency (MHRA)

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Current research shows tirzepatide often leads to greater average weight loss than semaglutide, though both drugs work well for many people

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