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189,190 NLGNs can participate in the formation of glutamatergic and GABAergic synapses in an activity-dependent manner

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This can show up as symptoms such as delayed growth and development (failure to thrive), regression in neuromotor skills (such as losing the ability to roll over or grasp objects), failure to maintain eye contact (even in an infant who previous could do so), general muscle weakness, lethargy, excessive sleepiness, feeding difficulties, and even brain shrinkage

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Accordingly, emerging drug strategies aim to restore synaptic function by enhancing activity-dependent synaptic plasticity or preventing synapse loss in these disorders

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A PubMed search for "pentadeca arginate" returns zero results

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