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Kwong B, Rua R, Gao Y, Flickinger J Jr, Wang Y, Kruhlak MJ, et al

Degradation can set in due to chemical reactions like oxidation, where exposure to oxygen breaks down the peptide structure

The functional activity of several proteins requires the presence of certain prosthetic groups covalently bound to the polypeptide chain

doi: 10.1101/cshperspect.a006189

Interleukin 6 is secreted by macrophages, T-helper lymphocytes, B lymphocytes, and astrocytes, and is effective on plasma cells and lymphocytes

56 Among them, GLUT4 is the best characterized and mediates glucose uptake in skeletal muscle and white adipose cells after insulin stimulation