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Such studies have shown BBB dysfunction in patients with AD and other neurodegenerative disorders such as PD, ALS, and MS, which is also supported by biofluid biomarker data and postmortem studies [190]

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High-glucose induces retinal pigment epithelium mitochondrial pathways of apoptosis and inhibits mitophagy by regulating ROS/PINK1/Parkin signal pathway

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Potential improvement in blood sugar control for those with type 2 diabetes