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Zeman SM, Phillips DR, Crothers DM

Those following a vegan diet must rely on their bodies to synthesize L-Carnitine from lysine and methionine, a process that primarily takes place in the liver and kidneys [5]

What they found: Prevention of age-related changes in gene expression , NMN-treated mice had an expression profile closer to young mice Restoration of mitochondrial function in multiple tissues Improvement of insulin sensitivity of 35 to 50 % Preserved muscle strength and endurance Preserved bone density Better vision (NMN-treated mice had a slower decline in ophthalmologic parameters) No serious adverse effects Why it matters: This is the most ambitious preclinical study of NMN/NAD+ in animal aging models

USP7 and TDP-43: Pleiotropic regulation of cryptochrome protein stability paces the oscillation of the mammalian circadian clock

Who It's For: Anyone looking to reduce signs of aging

Am J Med Gen