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Subgroup analysis based on GLP-1RA type showed that NNTB for albiglutide was 51, followed by semaglutide (NNTB 82), whilst the NNT for efpeglenatide, liraglutide, dulaglutide and exenatide was insignificant (Supplementary Material 4)

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Safer options include a high-fibre diet (aiming for 30g daily), regular physical activity (at least 150 minutes of moderate-intensity exercise weekly), portion control, and behavioural approaches such as mindful eating