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It is a reflection of how drug testing developed
These schedules often recommend initiating treatment with a very low dose and progressively increasing it, depending on the individuals tolerance to side effects
Think of it like going to the gym
[20:22] Andrew Huberman Maybe
In one study, repeated topical 5% DHA application in hairless dogs led to irritant contact dermatitis, with histopathological findings of epidermal thickening, degeneration, and inflammatory changes, while vehicle-only controls showed no such effects, indicating DHA as the causative agent
The transport of inorganic Se into the brain appears to be mainly responsible for Se neurotoxicity (Vinceti et al., 2014, 2016), implementing the U-shaped effects of Se on human health (Rayman et al., 2018
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