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Animals preconditioned with sphingosine-1phosphate (S1P), a bioactive lipid, demonstrated protection against inflammation, vascular permeability, oxidative damage, and brain tissue injury during acute and subchronic HH (67)

doi:10.1042/BJ20091541, PMID: 20025614 Aon MA, Cortassa S, ORourke B (2010) Redox-optimized ROS balance: a unifying hypothesis