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In models of NOS inhibitor-induced hypertension, BPC-157 attenuated blood pressure changes, suggesting interaction with the NO pathway rather than simple NO donation

Comment: A few commenters recommended modifications to the FMV documentation requirement to reduce administrative burden

Neuron 110 , 34583483 (2022)

426,432 Notably, the F508del CFTR delivered through the unconventional secretion pathway exhibits sufficient functionality, 429 suggesting that restraining ERAD and promoting trafficking of mutant forms of CFTR to the cell surface represent another therapeutic intervention targeting cystic fibrosis

Metal chelation Redox-active metal ions, such as free iron and copper, can induce oxidative damage by catalyzing reactions that generate highly reactive free radicals (20)

USA 104 , 52685273 (2007)