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Although the reasons for this partitioning are only partially understood, these antioxidants are considered critical in both health and disease

Wadden TA, Berkowitz RI, Womble LG, et al

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doi: 10.1016/j.joca.2005.10.010 43 AyukSMAbrahamseHHoureldNN

The development of next-generation oral GLP-1 agents with improved bioavailability enabling the higher systemic drug exposures needed to match injectable efficacy is the key technical milestone that will determine how much of the injectable market oral formulations can ultimately capture

A boxed warning is the most serious type of warning required by the Food and Drug Administration (FDA)