P38MAPK inhibition The p38MAPK inhibitor SB203580, by decreasing the transcriptional activity of NF-B, has been shown to reduce the levels of mRNA of genes of SASP factors in human senescent cells (81)
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*Correspondence: Yawei Cheng, [email protected] These authors have contributed equally to this work This article was submitted to Nutrition and Food Science Technology, a section of the journal Frontiers in Nutrition Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Elsewhere, estrogen exerts beneficial actions by suppression of reactive oxygen species (ROS)

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This hypoxic environment was maintained using a gas mixture (1% O 2 , 5% CO 2 , and 94% N 2 )