Consistent with the cell viability study, the two compounds with side chains on their 10 nitrogen, chlorpromazine and promethazine, exhibited significantly lower potencies against ROS generation with EC50s of 2148 and 9687 nM, respectively (Figure 4C, Table 1)
Three-chamber social behavioral analysis The three-chamber social test evaluated social motivation (010 min) and social novelty preference (1020 min) in experimental animals
V.ZehtabO.GuigoR.et al (2003)
In same model, AHG elevated phosphorylation levels of insulin receptor substrate-1(IRS1), Akt, and AMPK levels that were decreased by HFD treatment ( The Pueraria lobata polysaccharide (PLP) improved diabetic by scavenging blood glucose levels and alleviating the lipid metabolic function of db/db mice
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