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Follow these steps for best results: Prime the Bottle : Before first use, pump the spray 23 times into the air until a fine mist appears Clear Your Nose : Blow your nose gently to remove any blockage that could reduce absorption Tilt Your Head : Lean your head back slightly

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Mix gently until fully dissolved and a clear solution is obtained

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The original goal of the staple was to get the peptide into the cell, but it turns out the staple can also enhance the binding and enhance the specificity, Keating says