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Vitamin B12 is a water-soluble vitamin required for red blood cell production, DNA synthesis, and neurologic function

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Pharmacological Reviews, 59(2), 151184

However, understanding when high B12 levels may become problematic helps ensure safe, evidence-based supplementation under appropriate medical supervision

Therapeutic indications: Vitamin B 12 deficiency that cannot be corrected through a healthy diet

Time Series Analysis (TSA) using linear regression with repeated measures at 12, 24 and 36 months, was conducted to determine whether patient-reported persistence to OAC were independently associated with HRQOL