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regeneration should be performed promptly once the effluent quality exceeds acceptable limits, rather than being delayed for extended periods, which would only exacerbate contamination

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The phase 1 study in hereditary ATTR patients was prematurely terminated due to the COVID-19 pandemic, but preliminary data revealed that PRX004 was safe and alleviated disease progression in all seven assessable patients

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Depleted intracellular glutathione has been linked to Th1/Th2 immune imbalance and increased pro-inflammatory cytokine activity, which may contribute to autoimmune thyroid disease progression (Drge, 2002)

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