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1 Cardiovascular health scores are scientifically based measures of optimal cardiovascular health defined by the American Heart Association

Diabetes is more frequent in people of color, those who reside in rural regions, and those with less education, poorer incomes, and worse health literacy

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For example, a 2025 study in the Journal of the American Medical Association (JAMA) found people taking Ozempic were about 1.8 times as likely to experience vision loss from NAION, than those prescribed other diabetes medications

It has to be noted however that gain of function may also develop in parallel with loss of function, with reactive astrocytes for example losing their ability to clear glutamate in the context of motor neurone diseases