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All data were obtained from a minimum of five independent measurements, with each data point representing values derived from individual experimental animals

Taken together, these findings suggest that vitamin D exerts renal protection in CKD not only through inflammation, oxidative stress, and fibrosis regulation but also via its roles in autophagy, Klotho signaling, and podocyte stability, highlighting its broader therapeutic potential (Figure 3)

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Patients typically lose 10-15% of their body weight, with some achieving even greater losses

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These findings are more compatible with altered food valuation and reduced cue-driven motivation than with a primary change in basic gustatory processing