Cortisol reduces stomach acid levels, which interferes with the release and absorption of Vitamin B12 from food
Vitamin B12 deficiency can have serious medical consequences including irreversible neurological damage
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At a biological level, mononuclear counts increased, granulocytes decreased, and fibroblast, reticulin, and collagen fiber formation increased
Bulletin of experimental biology and medicine , 154 (3), 403410
If you plan to resume, restart at the full dose rather than titrating back up, since the break period allows receptor resensitization