4 Because levothyroxine has a narrow therapeutic range, where too little brings thyroid symptoms back, and too much can cause palpitations, anxiety, or sleep problems, the sensible approach is to keep your usual timing, monitor your blood tests, and inform your prescriber of any symptoms you experience
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On the other hand, in another study of PSD, a high dose of caffeine impairs memory and leads to an anxiogenic and depressive-like behavior in the hole board and elevated plus maze tests, and social interaction and locomotor activity, respectively, also increased pro-inflammatory cytokines such as TNF-alpha and IL-6 [37]
JA conceived the article, contributed additional text, and edited the manuscript throughout for content and style consistency
