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doi:10.1093/annonc/mdw027 2

IF/FISH showing localization of H2AX and Telomeres within immune cells isolated from young-adult (8 week old) and aged-adult (17 week old) individuals

During the 1990s, drug companies were also working on their own GLP-1 agonists

Liver & Metabolic Benefits Emerging data show that GLP-1 RAs may: Reduce hepatic fat accumulation (Anti-steatotic effect) Slow fibrosis progression (Anti-fibrotic effect) Improve insulin sensitivity and lipid profile Lower cardiovascular risk through endothelial protection In NAFLD/NASH, trials like LEAN, STEP, and SURPASS demonstrate improvements in liver histology, ALT/AST reduction, and fibrosis regression even independent of weight loss

Sometimes lifestyle changes are enough to improve appetite, energy, and weight patterns

For now, at least