The decision depends on weight loss progress, side effects, health markers, maintenance planning and provider guidance
Buysschaert M, Baeck M, Preumont V, Marot L, Hendrickx E, Van Belle A, et al
Combined with rapid weight loss, this can cause significant muscle breakdown
Furthermore, the convenience of a once-weekly subcutaneous injection makes semaglutide an appealing option for many patients
Study #2: Menstrual cycle regularity The same meta-analysis found significant improvement in menstrual regularity (SMD: 1.72, P 15 pounds during washout: This suggests intervention needed: Reassess calorie intake (are you eating significantly more than maintenance?) Increase protein target to 120-150g daily Add resistance training if not already doing it Consider extended washout (4 months instead of 3) to stabilize weight Meet with dietitian for structured meal plan Important consideration: Significant weight regain may impact the fertility improvements you gained from GLP-1 use
You can read the full article at Cardiovascular risk reduction with once-weekly semaglutide in subjects with type 2 diabetes: a post hoc analysis of gender, age, and baseline CV risk profile in the SUSTAIN 6 trial PMC (nih.gov)