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In clinical trials, patients typically lose 15-20% of their body weight

Natriuretic effect by exendin-4, but not the DPP-4 inhibitor alogliptin, is mediated via the GLP-1 receptor and preserved in obese type 2 diabetic mice

Zhang Y, Zhang Q, Bai Y, Zheng H, Ji L, Zhu X et al (2023) Glycogen synthesis kinase-3 involves in the analgesic effect of liraglutide on diabetic neuropathic pain

This has led to some pharmacists stopping the sale of brand-name drugs altogether

Effects of Obesogenic Feeding and Free Fatty Acids on Circadian Secretion of Metabolic Hormones: Implications for the Development of Type 2 Diabetes. Cells, vol