Some promising approaches include the following: - Garlic-derived allicin: reduces TMAO in murine models (C57BL/6 mice), suggesting anti-atherosclerotic potential ( - TMA lyase inhibitors: synthetic compounds (e.g., fluoromethylcholine, FMC) that irreversibly inhibit CutC/D (Roberts et al., 2018)
Talazoparib in patients with advanced breast cancer and a germline BRCA mutation
Recovery typically requires 12 weeks, after which metabolic management can proceed without gallbladder-specific constraints
Maneva, A., Taleva, B
Thus, pandemics and epidemics are recurrent, and more are likely to follow in the future, in particular, due to human impact on the global environment 6,7
Gillingham M, Van Calcar S, Ney D, Wolff J, Harding C: Dietary management of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD)