[DOI] [PubMed] [Google Scholar] Wilson ME, Scheel D, German MS
Current evidence supports the safety profile of GLP-1 medications when prescribed appropriately, with benefits in glycaemic control and cardiovascular risk reduction generally outweighing theoretical thyroid concerns for most patients
In cases of confirmed, severe gastroparesis attributable to GLP-1 therapy, medication discontinuation is generally recommended, consistent with FDA labeling that these agents are not recommended for patients with severe gastroparesis
What actually is GLP-1
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However, compared with, for example, the area postrema, the arcuate nucleus receives stronger innervation from PPG neurons (Gu et al., 2013