Notably, SCFAs act as critical signaling metabolites that activate G-proteincoupled receptors (GPCRs), thereby suppressing pro-inflammatory cytokine production and promoting regulatory T-cell expansion within the colonic mucosa (301)
Wrights research revealed that, among other things, Glutathione on its own was effective in significantly reducing in the blood-sugar levels of the diabetic rats, which were administered the compound
Moreover, it has been shown that OLE and HTyr activate autophagy in SH-SY5Y cells exposed to toxic A142 oligomers, thus preventing the accumulation of ROS and the impairment of mitochondrial function [140]
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doi: 10.1038/s41420-023-01369-2 10 YuanCMaZXieJLiWSuLZhangGet al