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This article aims to provide a detailed comparison of these two medications, answering some of the most common questions people have about them

Patients with certain genetic profiles may tolerate one medication better than the other, despite both drugs having identical safety profiles in the general population

GLP-1 RAs should replace metformin in the type 2 diabetes algorithm

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This chimeric structure distinguishes them from a separate class of dual- or tri- agonist molecules in which conjugation strategies involving synthetic linker chemistry are used to fuse the full-length amino acid sequences of peptides such as the hormones glucagon, GLP-1, gastrin, and gastric inhibitory polypeptide (GIP) 1,2,3,15

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